Billionaire Profile
David Dean Halbert
Global Rank
#1208

Image: Public domain | via Wikimedia Commons

David Dean Halbert

CEO, Caris Life Sciences
US
Real-Time Net Worth
$3.3B
As of December 2025
Age
69
Source
Biotech
Industry
healthcare
Citizenship
US

Biography

David Dean Halbert is a prominent American entrepreneur and philanthropist, currently ranked #308 on the Forbes 400 list (2025). Born in 1956, Halbert's source of wealth is primarily derived from the biotechnology sector. He is the founder, Chairman, and CEO of Caris Life Sciences, a pioneering precision medicine company. Halbert's career includes founding AdvancePCS in 1987, a pharmacy benefit manager sold for $7.5 billion in 2004. He is an alumnus of Abilene Christian University, holding a Bachelor of Business Administration and an honorary Doctorate of Science. Halbert is known for his dedication to advancing healthcare and his philanthropic efforts, including the Caris Foundation, supporting various causes in Haiti and Africa. He is married and has three children. In 2024, his estimated net worth is $3.3 billion.

Wealth Over Time

In-Depth Profile

Early Life and Education

David Dean Halbert was born in Abilene, Texas, in 1956. He graduated from Abilene Christian University in 1978 with a Bachelor of Business Administration degree. Halbert's upbringing and education instilled in him a strong sense of stewardship and a commitment to using his resources effectively.

Rise to Success

Halbert's entrepreneurial journey began with the founding of AdvancePCS in 1987, a pharmacy benefit management company. As Chairman and CEO, he led the company's growth, transforming it into a publicly traded Fortune 250 corporation with over $15 billion in annual revenue. AdvancePCS was later sold to Caremark in 2004 for $7.5 billion. In 2005, he formed Caris Capital. Halbert then founded Caris Life Sciences in 2008, initially acquiring Molecular Profiling Institute (MPI), and expanding it into a major player in precision medicine. In June 2025, Halbert became a billionaire when Caris Life Sciences went public.

Key Business Strategies

Halbert's success stems from his ability to identify opportunities in the healthcare sector and his focus on innovation. At AdvancePCS, he expanded the company through strategic acquisitions and a focus on improving healthcare while reducing costs. At Caris Life Sciences, he pioneered the use of gene sequencing and AI to advance early disease detection.

Philanthropy

Halbert and his family established the Caris Foundation in 2002, which supports impoverished communities by providing for their basic needs. The foundation has been involved in significant initiatives, including a $98.5 million investment by USAID to bolster Haiti's health system. In 2014, Halbert donated $15 million through the Caris Foundation to Abilene Christian University for the Halbert-Walling Research Center.

Career Milestones

1987

Founded AdvancePCS

Founded a pharmacy benefit manager that grew to become a major player in the industry.

2004

Sold AdvancePCS

Sold AdvancePCS to Caremark for $7.5 billion.

2005

Founded Caris Capital

Founded an investment firm.

2008

Founded Caris Life Sciences

Founded a company focused on precision medicine.

2025

Caris Life Sciences IPO

Caris Life Sciences went public, making Halbert a billionaire.

Philanthropy & Social Impact

Education

Caris Foundation

$15M

Provided funds for the Halbert-Walling Research Center at Abilene Christian University.

Humanitarian Aid

Caris Foundation

Undisclosed

Supports impoverished people in Haiti and Africa.

Healthcare

Project Santé

$98.5M

Involved in a USAID investment to bolster Haiti's health system.

Business Philosophy & Leadership

Notable Quotes

"I fundamentally believed that if there was something wrong with the human body, there was something misfiring at the molecular level and technology advances could find that and diagnose it and possibly treat it."

Leadership Principles

Commitment to Precision Medicine

Advocating for more precise and individualized health information to improve the quality of care patients receive.

Stewardship

Using resources to the best of ability.