Billionaire Profile
Lee Sang-hoon
Global Rank
#2292

Image: Public domain | via Wikimedia Commons

Lee Sang-hoon

CEO, ABL Bio
US
Real-Time Net Worth
$1.5B
As of December 2025
Age
62
Source
Biotech
Industry
healthcare
Citizenship
US

Biography

Lee Sang-hoon is a South Korean biotech entrepreneur, currently serving as the founder, chairman, CEO, and chief research officer of ABL Bio. ABL Bio specializes in developing bispecific antibodies aimed at improving treatment outcomes for cancer and neurodegenerative diseases. Born in 1963, Lee's career includes leadership roles at various companies, including AstraZeneca, Genentech, and Exelixis. He founded ABL Bio in 2016, which was later listed on Korea's Kosdaq stock exchange in 2018. His net worth is estimated at $1.5 billion as of November 2025, primarily stemming from his success in the biotech sector.

Wealth Over Time

In-Depth Profile

Early Life and Education

Lee Sang-hoon was born in South Korea in 1963. From 1982 to 1989, he pursued his studies at Seoul National University, where he earned a Bachelor of Science followed by a Master's degree in developmental biology. He furthered his education by completing a Ph.D. in Molecular, Cellular and Developmental Biology at Ohio State University in 1994. He also completed postdoctoral fellowships at Harvard Medical School, the University of California, San Francisco, and Stanford Medical School.

Rise to Success

Lee's career began with research positions at prominent companies in the biotech industry, including AstraZeneca, Genentech, and Exelixis. In 2008, he co-founded PharmAbcine, playing a key role in research and development for antibody therapeutic projects. He also served as the head of the bio division at Hanwha Chemical. In 2016, Lee founded ABL Bio, which became a significant venture. ABL Bio's listing on the KOSDAQ in 2018 marked a major milestone.

Key Business Strategies

ABL Bio focuses on developing bispecific antibodies that target two molecules simultaneously. This approach aims to improve treatment outcomes for diseases like cancer and neurodegenerative conditions. ABL Bio's strategy involves a diverse portfolio of bispecific antibody-based treatments. A significant achievement includes the 2025 technology-transfer deal with Eli Lilly, valued at $2.6 billion, related to ABL Bio's Grabody-B blood-brain-barrier-penetrating bispecific antibody technology.

Philanthropy

While specific details about his philanthropic activities are not readily available, Lee's commitment to innovation in biotechnology suggests a broader vision for improving health outcomes.

Career Milestones

2008

Co-founded PharmAbcine

Co-founded PharmAbcine where he oversaw all research and development for antibody therapeutic projects.

2016

Founded ABL Bio

Founded ABL Bio, a biotechnology company specializing in bispecific antibodies.

2018

ABL Bio Listed on KOSDAQ

ABL Bio was listed on Korea's Kosdaq stock exchange.

2025

Technology Transfer Deal with Eli Lilly

ABL Bio signed a $2.6 billion technology-transfer deal with Eli Lilly related to ABL Bio's Grabody-B blood-brain-barrier-penetrating bispecific antibody technology.