Billionaire Profile
Wayne Rothbaum
Global Rank
#1402

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Wayne Rothbaum

CEO, Biotech investing
UNITED STATES
Real-Time Net Worth
$2.955B
Estimated based on Biotech investing stock value as of March 6, 2026
+0.48% (24h)
Age
57
Source
Biotech investing
Industry
Finance & Investments
Citizenship
UNITED STATES

Biography

Wayne Rothbaum is a highly successful American biotech investor with an estimated net worth of $2.6 billion as of February 2, 2026. Rothbaum, 57, is known for his strategic investments and founding of Quogue Capital in 2001, a life sciences investment fund. His career is marked by a focus on biotech, notably co-founding and being the largest investor in Acerta Pharma, which was later acquired by AstraZeneca. Rothbaum's approach involves in-depth research and conviction in the potential of a drug or company, which has led to significant returns. He is also a board member and the largest shareholder of Iovance Biotherapeutics.

Fact Checked
Verified by Editorial Team
Live Data
Updated 3/6/2026

Wealth Over Time

In-Depth Profile

Early Life

Wayne Rothbaum was born in 1968 and grew up in Smithtown, Long Island. His father co-owned a small security business, and the family faced financial struggles. Rothbaum attended Binghamton University, initially intending to study medicine before switching to political science and psychology. He later earned a master's degree in international affairs from George Washington University.

Rise to Success

Rothbaum's career began in finance. In the early 1990s, he joined the Carson Group, a consulting firm advising biotech companies and investors. Despite a lack of a formal science background, he immersed himself in biology and molecular medicine. He then helped launch the firm's investment banking division.

In 2001, Rothbaum founded Quogue Capital, a single-family office, which allowed him to invest his own money with his own strategies. He became a prominent biotech investor. In 2012, Rothbaum co-founded and was the largest investor in Acerta Pharma, which developed the blood cancer drug Calquence. Rothbaum's conviction-driven investment approach allowed him to identify promising companies and make significant returns.

Key Business Strategies

Rothbaum's investment strategy centers on in-depth research, strong conviction, and a willingness to take risks. He often invested in companies with promising drugs or technologies. Rothbaum avoids diversification, preferring to make concentrated investments in ventures he believes in.

Rothbaum's involvement extended beyond financial investment; he would actively participate in the restructuring of companies, and closely monitor clinical trials. His approach includes meticulous analysis of data and the ability to identify the potential of a company, even when it is not immediately apparent to others. He makes big bets that can really count.

Philanthropy

Wayne Rothbaum has demonstrated his commitment to philanthropy by donating $300 million to SUNY Binghamton for a sports complex and scholarships, and to Ohio State University to build housing for cancer patients.

Career Milestones

2001

Founded Quogue Capital

Established his life sciences investment fund.

2012

Cofounded Acerta Pharma

Became the largest investor in the cancer drug developer.

2016

Executive Chair Kartos Therapeutics

Cofounded cancer drug firm.

2016

Director of Iovance Biotherapeutics

Became a board member and the largest shareholder.

2019

Cofounded Telios Pharma

Founded cancer drug firm.

Philanthropy & Social Impact

Education

SUNY Binghamton Donation

$300M

Donated for a sports complex and scholarships.

Healthcare

Ohio State University Donation

$300M

Donated to build housing for cancer patients.

Business Philosophy & Leadership

Notable Quotes

"If you believe in a drug a company or a trial you go for it you don't wait for consensus."

Leadership Principles

Conviction

Making informed decisions based on a deep understanding of the science and market.

Focus

Concentrating investments in a few high-potential opportunities.

Action

Willingness to take action and make big bets.