Billionaire Profile
Phillip Frost
Global Rank
#1834

Image: Public domain | via Wikimedia Commons

Phillip Frost

CEO, OPKO Health, Inc.
US
Real-Time Net Worth
$2.1B
As of December 2025
Age
89
Source
Pharmaceuticals
Industry
healthcare
Citizenship
US

Biography

Phillip Frost, born around 1936, is an American entrepreneur renowned for his significant contributions to the pharmaceutical and healthcare industries. With a net worth of $2.1 billion, Frost's wealth stems primarily from his ventures in pharmaceuticals. His career is marked by pivotal achievements, including founding and leading Key Pharmaceuticals, Ivax Corporation, and OPKO Health. His journey showcases his entrepreneurial spirit and commitment to innovation. Frost also made important contributions to dermatology. He is known for his significant philanthropic efforts, donating to educational, scientific, and cultural institutions.

Wealth Over Time

In-Depth Profile

Early Life and Education

Phillip Frost was born into an observant Jewish family in the United States around 1936. At the age of 13, he began working at a local hardware shop. He earned a Bachelor of Arts in French literature from the University of Pennsylvania in 1957 and received an M.D. from the Albert Einstein College of Medicine in 1961. He also studied at the University of Paris from 1955 to 1956.

Rise to Success

Frost's career includes significant roles in the pharmaceutical sector. He served as chairman and CEO of Ivax Corporation from 1987 until its acquisition by Teva in January 2006. He was also chairman of Key Pharmaceuticals, from 1972 until its acquisition by Schering-Plough in 1986. Frost became vice chairman of Teva Pharmaceutical Industries in January 2006, and later chairman of the board in March 2010, stepping down in 2015. He is currently the CEO and Chairman of OPKO Health, Inc. since March 2007.

Key Business Strategies

Frost's business strategies have been characterized by strategic acquisitions, innovative product development, and a keen eye for market opportunities. He has a strong presence in the healthcare industry and a history of founding and leading several successful companies, including Key Pharmaceuticals and Ivax Corporation. His leadership at OPKO Health, and investments in various biotechnology companies, highlight his commitment to advancing medical innovation and technology.

Philanthropy

Frost is known for his philanthropic contributions, particularly in science, education, and the arts. He and his wife, Patricia, have supported the University of Miami, funding the Phillip and Patricia Frost School of Music, the Phillip and Patricia Frost Institute for Chemistry & Molecular Sciences, and the Phillip Frost Department of Dermatology. They also contributed to the Phillip and Patricia Frost Museum of Science. In 2011, they contributed $35 million to fund the construction of the new Miami Science Museum building.

Career Milestones

1966

Professor of Dermatology

Appointed professor of dermatology at the University of Miami School of Medicine.

1972

Chairman of Key Pharmaceuticals

Bought Key Pharmaceuticals, Inc. with Michael Jaharis.

1987

Founder of Ivax Corporation

Founded Ivax Corporation, a generic drugmaker.

2007

CEO and Chairman of OPKO Health

Became CEO and Chairman of OPKO Health, Inc.

Philanthropy & Social Impact

Education

University of Miami Support

$100M

Donated to STEM programs at the University of Miami.

Arts

Frost School of Music

$33M

Gifted for the music program at Florida International University.

Science

Frost Museum of Science

$45M

Contributed to the Phillip and Patricia Frost Museum of Science.

Controversies & Challenges

2018

SEC Charges

Charged by the SEC with participating in a "pump and dump" scheme.